Boldenone ikhoza kutembenuzidwa kukhala estrogen koma yocheperapo kuposa testosterone, kuwonjezera apo, boldenone imapangidwa ndi 1,4 dienedione yomwe ndi yolimba ya aromatase inhibitor.Boldenone imatembenuzidwa ndi 5-alpha reductase ku 1-testosterone, steroid yamphamvu kwambiri komanso 5-beta isomer yomwe imaganiziridwa kuti ndi metabolite yosagwira ntchito.Kumangiriza ku SHBG ndikotsika kwambiri ndi boldenone kuposa ndi testosterone kutanthauza kuti ndende ya plasma yaulere koma yayifupi ndi theka la moyo mu plasma.Palibe chomangirira pang'ono ku progesterone kapena glucocorticoid receptors ndipo palibe deta yeniyeni yokhudzana ndi boldenone ndi machitidwe osiyanasiyana a enzyme.

Boldenone imachita zofanana ndi methandrostenolone ndi zotsatira zochepa za androgenic.Ili ndi theka la moyo wautali kwambiri, ndipo imatha kuwonetsa mayeso a steroid mpaka miyezi 5, chifukwa cha ester yaundecylenate yayitali yomwe imalumikizidwa ndi kholo la steroid.Kufufuza kuchuluka kwa mankhwala mosavuta wapezeka kwa miyezi anasiya ntchito.

Ngakhale kuti kawirikawiri poyerekeza ndi nandrolone, boldenone ilibe kuyanjana kwa progesterone receptor ndi zotsatira zonse zogwirizana ndi progestogenic.